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Coronary heart disease (CHD) is a generic designation for a group of related syndromes resulting from myocardial ischemia – an imbalance between cardiac blood supply (perfusion) and myocardial oxygen demand. Visfatin (VF)  is a recently discovered adipokine with different functions, Visfatin is mainly found in visceral adipose tissue and mimics insulin in lowering plasma glucose levels and, Visfatin emerges as a player in the development and progression of atherosclerotic lesions by directly promoting smooth muscle cell proliferation, Aberrant angiogenesis is now considered a feature of the atherogenic process in both coronary and carotid diseases. This adipokine was previously known as a pre-B-cell colony-enhancing factor   (PBEF) or  Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) an enzyme that in humans is encoded by the NAMPT gene  and demonstrated to be an intracellular protein with a key enzyme role in nicotinamide adenine dinucleotide (NAD)


Coronary heart diseases Visfatin adipokine pre-B-cell colony-enhancing factor (PBEF)

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How to Cite
Al-Kraity, A. P. D. W. R. H., Faisal, A. H., Khaleel, A. N., Naeaam, M. T., & Jabar, A. S. (2021). Description of Visfatin Adipokine and its Roles on Inflammation and Coronary Heart Disease: A Review Study. Medical Science Journal for Advance Research, 2(1), 10–14.


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