Evaluation of the Analytical Value of ECG-Derived Tpeak-Tend Interval in Hypertensive Patients in the Babylon Governorate
DOI:
https://doi.org/10.46966/msjar.v7i2.407Keywords:
Tpeak-Tend interval, QTc, hypertension, ventricular repolarisation, electrocardiographyAbstract
Background: Hypertension remains one of the most prevalent global health challenges and is widely recognised as a primary risk factor for a spectrum of cardiovascular diseases.
Aim: This study aimed to investigate the prevalence of ventricular repolarisation abnormalities and conduction system irregularities in patients with systemic arterial hypertension
Methods: The analysis was performed using standard 12-lead electrocardiogram (ECG) recordings at paper speed of 25 mm/s and amplitude of 10 mm/mV. Heart rate and QRS duration were derived from automated ECG reports. QT, RR and Tpe intervals were assessed with semi-automated digital software. Only patients who had sinus rhythm were included.
Results: Compared to the control group subjects, patients had statistically significant prolongations of QTd, QTc and Tpe intervals (p < 0.05). The higher prevalence of abnormal values was seen for the Tpe and corrected Tpe intervals (94% and 100%) than it was in the QTc interval (52%). In the hypertensive group, comparison analyses showed a strongly positive correlation between QT/QTc intervals and Tpe, TpecBa, and TpecFd (p < 0.001).
Conclusion: The corrected Tpeak-Tend interval with Bazett’s or Fridericia’s formulae may be a useful marker for evaluating the variability of ventricular repolarisation in hypertensive patients. The significant Tpe and QTc interval prolongation in the results implies that these patients have an increased risk of repolarisation dispersion leading to cardiac arrhythmias.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Ekhlas Hatem AL-Asadi, Hawraa Hamid Hussein, Ahlam Kadhim Abbood
This work is licensed under a Creative Commons Attribution 4.0 International License.
In submitting the manuscript to the Medical Science Journal for Advance Research, the authors certify that:
- They are authorized by their co-authors to enter into these arrangements.
- The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
- That it is not under consideration for publication elsewhere,
- The publication has been approved by the author(s) and by responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
- They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
- They agree to the following license and copyright agreement.
License and Copyright Agreement
Authors who publish with Medical Science Journal for Advance Research agree to the following terms:
- Authors retain copyright and grant the Medical Science Journal for Advance Research right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the Medical Science Journal for Advance Research published version of the work (e.g., post it to an institutional repository or edit it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
