The Influence of Viral Hepatitis C Infection on Some Biochemical Markers in Patients with Chronic Renal Failure in Najaf Province, Iraq

Abstract

The objective of this study was to assess the impact of HCV on various biochemical markers, including Vit-D, PTH, CA, and iron, and to compare these effects with individuals with chronic kidney disease (CKD) but without HCV. Methods: 80 patients with chronic kidney disease (CKD) who were undergoing dialysis were enlisted for this study. Among them, 37 patients tested positive for HCV, while 43 patients tested negative for HCV. Their sera were collected and subjected to the necessary biochemical marker tests. Statistical analysis was performed using SPSS Results: The levels of Vitamin D, iron, calcium, and phosphorus did not show any notable disparity between the two groups. The only significant difference seen was in PTH levels, with greater results observed in CKD with HCV infection. Implications: : The possibility exists for the Hepatitis C virus (HCV) to worsen the status of patients diagnosed with chronic kidney disease (CKD). Nevertheless, the intervention did not yield a substantial effect on the concentrations of specific pivotal indicators associated with mineral metabolism, except parathyroid hormone.